Bone Marrow Transplantation
Bone Marrow Transplantation
We are the pioneers and a leading centre dedicated to providing comprehensive and advanced care for patients requiring bone marrow transplantation. Our team comprises experienced haematologists, oncologists, and specialised nurses who work collaboratively to deliver the highest standards of patient care. We offer a wide range of transplantation options tailored to meet the unique needs of each patient, including adult and paediatric transplants.
1. Autologous Bone Marrow Transplantation
Autologous BMT involves harvesting a patient’s own stem cells prior to intensive chemotherapy or radiation therapy. This procedure is primarily used to treat certain cancers and blood disorders. Our capabilities include:
- Multiple Myeloma: High-dose chemotherapy followed by reinfusion of the patient’s own stem cells.
- Lymphomas: Treatment for relapsed or refractory Hodgkin and non-Hodgkin lymphomas.
- Solid Tumours: Used in certain cases such as neuroblastoma and germ cell tumours.
2. Allogeneic Bone Marrow Transplantation
Allogeneic BMT involves using stem cells from a donor, which can be a family member. This type of transplant is used to treat various hematologic malignancies and disorders. Our services include:
- Leukaemia: Treatment for acute and chronic types including AML, ALL, CML, and CLL.
- Myelodysplastic Syndromes (MDS): Utilising donor stem cells to replace diseased bone marrow.
- Bone Marrow Failure Syndromes: Including severe aplastic anaemia and Fanconi anaemia.
- Inherited Metabolic Disorders: Such as Hurler syndrome and other lysosomal storage diseases.
- Hemoglobinopathies: Including thalassemia major and sickle cell disease.
3. Haploidentical Bone Marrow Transplantation
Haploidentical BMT uses a partially matched related donor from a family member. This method has expanded the donor pool and is increasingly used due to advancements in post-transplant care. Our expertise includes:
- Graft-Versus-Host Disease (GVHD) Management: Utilising innovative approaches to minimise GVHD.
- High-Dose Cyclophosphamide: Post-transplant to reduce the risk of graft rejection and GVHD.
- Rapid Immune Recovery: Ensuring quicker recovery of the immune system to reduce infection risks.
Specialized Pediatric Bone Marrow Transplantation
Our paediatric BMT unit offers specialised care for children requiring bone marrow transplants. We provide child-friendly environments and tailored medical protocols to ensure the best possible outcomes for our young patients. Key areas include:
- Paediatric Leukaemia: Treatment for various types of leukaemia including high-risk cases.
- Congenital Bone Marrow Failure Syndromes: Such as Diamond-Blackfan anaemia and Shwachman-Diamond syndrome.
- Immunodeficiency Disorders: Including severe combined immunodeficiency (SCID) and Wiskott-Aldrich syndrome.
Comprehensive Care Approach
The BMT Department at NIBD adopts a holistic approach to patient care, encompassing:
- Pre-Transplant Evaluation: Thorough assessments to determine the most appropriate type of transplant.
- Conditioning Regimens: Tailored conditioning therapies to prepare patients for transplantation.
- Post-Transplant Care: Intensive monitoring and support to manage complications and ensure recovery.
- Long-Term Follow-Up: Ongoing care to monitor for late effects of transplantation and maintain health.
Advanced Support Services
Our department is supported by a range of specialised services to ensure comprehensive care:
- Infectious Disease Management: Specialised care to prevent and treat infections in immunocompromised patients.
- Psychosocial Support: Providing counselling and support for patients and their families throughout the transplant journey.
- Nutritional Support: Tailored nutrition plans to support recovery and overall health.
- Physical Rehabilitation: Programs to help patients regain strength and mobility post-transplant.
At NIBD, we are committed to advancing the field through continuous research, innovation, and a patient-centred approach. Our goal is to provide every patient with the best possible chance for a successful transplant and a return to a healthy life.